Seth Woodbury MacFarlane (born October 26, 1973) is an American animator, writer, comedian, producer, actor, singer, voice actor, and director best known for creating the animated sitcoms Family Guy, American Dad! and The Cleveland Show, for which he also voices many of the shows' various characters.

A native of Kent, Connecticut, MacFarlane is a graduate of the Rhode Island School of Design, where he studied animation, earning a Bachelor of Fine Arts Degree. He was an animator and writer for Hanna-Barbera for several television shows, including Johnny Bravo, Cow and Chicken and Dexter's Laboratory, before creating his own series for 20th Century Fox entitled Family Guy in 1999. MacFarlane would go on to co-create American Dad! in 2005, The Winner in 2007 and The Cleveland Show in 2009 for 20th Century Fox.

As an actor, he has made guest appearances on shows such as Gilmore Girls, The War at Home and FlashForward. MacFarlane's interest in science fiction and fantasy has led to cameo and guest appearances on Star Trek: Enterprise and voicing the character of Johann Kraus in Guillermo del Toro's Hellboy II: The Golden Army. In 2008, he created his own YouTube series entitled Seth MacFarlane's Cavalcade of Cartoon Comedy. As a performer, MacFarlane has sung at several venues, including Carnegie and Royal Albert Hall.

MacFarlane has won several awards for his work on Family Guy, including two Primetime Emmy Awards, and an Annie Award. In 2009, he won the Webby Award for Film & Video Person of the Year. He has been a subject of criticism from television watchdog groups, such as the Parents Television Council, who regularly condemn Family Guy for its indecency. He occasionally speaks at universities and colleges throughout the United States, and is a supporter of gay rights.

On the February 10, 2011 episode of the TBS variety nighttime talk-show series Conan, MacFarlane announced he is directing his first feature-length film, Ted. The film stars Mark Wahlberg as an adult, who as a child, wished his teddy bear would come to life. MacFarlane will be the voice and motion capture for the bear.

2008: Johann (voice) - Hellboy II: The Golden Army
2010: Ziggy - Tooth Fairy
2007: Emperor Palpatine (voice) - Robot Chicken: Star Wars
2008: Emperor Palpatine / Dr. Ball / Figrin D'an (voice) - Robot Chicken: Star Wars Episode II
2006: Dr. Ned - Life Is Short
2010: Emperor Palpatine (voice) - Robot Chicken: Star Wars Episode III
2012: Ted (voice) - Ted
2011: Himself - Seth MacFarlane: Swingin' in Concert
2013: Seth MacFarlane (segment - Movie 43
2014: Albert Stark - A Million Ways to Die in the West
1995: Seth MacFarlane / Larry Cummings / Steve / Lois Cummings / Man in Underwear / Captain Kirk / Mr. Spock / Sulu / Ensign Skippee / British Man / Jeremy / Tom Hanks / Alex Trebek / Preacher / God (voice) - The Life of Larry
2011: Peter Griffin as Han Solo / Stewie Griffin as Darth Vader / Brian Griffin as Chewbacca / Glenn Quagmire as C-3PO / Carter Pewterschmidt as Emperor Palpatine / Roger as Moff Jerjerrod / Tim the Bear as Wickett / A Live Ostrich (voice) - Family Guy Presents: It's a Trap!
2015: Ted (voice) - Ted 2
2011: Himself - Roastmaster - Comedy Central Roast of Charlie Sheen
2009: himself - Family Guy Presents: Seth and Alex's almost live comedy show
2010: Himself - Comedy Central Roast of David Hasselhoff
2016: Mike (voice) - Sing
2015: Sinatra 100: An All-Star Grammy Concert
2011: Himself - Comedy Central Roast of Donald Trump
2017: Max Chilblain - Logan Lucky
2014: Various - Robot Chicken: Christmas Specials
2014: Santa Claus (voice) - The Robot Chicken Lots of Holidays (But Don't Worry Christmas is Still in There Too So Pull the Stick Out of Your Ass Fox News) Special
2005: Peter Griffin, Stewie Griffin, Brian, Glen Glenn Quagmire, Tom Tucker, Stuart Griffin, Bugs Bunny (voice) - Family Guy Presents Stewie Griffin: The Untold Story
1996: Larry/Steve (voice) - Larry and Steve
2009: Mars Vegas Singer (singing voice) - Futurama: Into the Wild Green Yonder
2017: Himself - The Truth Is in the Stars
2007: Peter Griffin as Han Solo / Brian Griffin as Chewbacca / Stewie Griffin as Darth Vader / Glenn Quagmire as C-3PO / Tom Tucker as Imperial Newscaster / Carter Pewterschmidt as Uncle Owen / Additional Voices (voice) - Family Guy Presents: Blue Harvest
2010: I.S.R.A.E.L. (aka Intelligent Smart Robotic Animated Eraser Lady) (voice) - The Drawn Together Movie: The Movie!
2010: Himself - The Simpsons 20th Anniversary Special – In 3-D! On Ice!
2017: Himself - Gwen Stefani's You Make It Feel Like Christmas
2011: Family Guy Presents: Road to the North Pole
2008: A Very Special Freakin Family Guy Christmas
2009: Family Guy Presents: Stewie Kills Lois and Lois Kills Stewie
Untitled Family Guy live-action/animated film
2021: Mike - Sing 2
2009: Peter Griffin as Han Solo / Brian Griffin as Chewbacca / Stewie Griffin as Darth Vader / Glenn Quagmire as C-3PO / Dr. Elmer Hartman as General Rieekan / Carter Pewterschmidt as Emperor Palpatine (voice) - Family Guy Presents: Something, Something, Something, Dark Side

2001: Engineer - Star Trek: Enterprise
2005: Lion-O - Robot Chicken
2005: American Dad!
2000: Gilmore Girls
2008: Seth MacFarlane's Cavalcade of Cartoon Comedy
2000: Aqua Teen Hunger Force
2006: Talkshow with Spike Feresten
2002: 3 South
2005: Robot Chicken
1999: Family Guy
2003: Jimmy Kimmel Live!
2004: Complete Savages
1996: The Daily Show with Trevor Noah
2005: Too Late with Adam Carolla
1995: MADtv
2009: FBI Agent - FlashForward
1999: Himself - Teen Choice Awards
2009: Agent Jake Curdy - FlashForward
2005: Stan Smith / Roger (voice) - American Dad!
2009: Tim the Bear (voice) - The Cleveland Show
2015: Himself - StarTalk with Neil deGrasse Tyson
1953: Seth MacFarlane - The Academy Awards
2014: Giordano Bruno (voice) - Cosmos
1999: Peter Griffin / Brian Griffin / Stewie Griffin / Glenn Quagmire / Tom Tucker / God / Kool-Aid Guy (voice) - Family Guy
2017: Ed Mercer - The Orville
2017: Himself - Carpool Karaoke
2003: Radio Announcer (voice) - The Pitts
2003: Movie Dad (voice) / Son (voice) - The Pitts
2019: Brian Lewis - The Loudest Voice
2001: Ensign Rivers - Star Trek: Enterprise
1997: Himself - The View
2003: Himself - Real Time with Bill Maher